The Todmorden Mills Museum is located on Pottery Road, just west of Broadview Avenue at Mortimer Avenue. To access the site from the Don Valley Parkway, take the Bayview/Bloor Street exit, then follow Bayview Avenue north to Pottery Road.

To access the site by Toronto Transit (TTC), from the Broadview subway station, take any northbound bus to Pottery Road. The Museum is a short walk down Pottery Road, in the Don Valley.